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Portada volumen 28, nº 2 de 2025
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January 7, 2025
Published
June 30, 2025
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Abstract

Introduction: The use of tunneled central venous catheters in haemodialysis is frequently associated with catheter-related bacteraemia. The closed-system connector with a neutral valve emerges as an alternative to reduce this risk by limiting manipulation of the catheter lumen.


Objectives and Hypothesis: To evaluate whether the systematic use of closed-system connectors with a neutral valve decreases the rate of catheter-related bacteraemia. It was hypothesised that its use would significantly reduce both complications.


Material and Method: We conducted a retrospective, quasi-experimental, before-after study in a regional hospital over 12 months. A total of 62 catheters in 55 patients were included. Rates of catheter-related bacteraemia per 1,000 catheter-days were evaluated, in addition to parameters on catheter function. Statistical tests for proportion comparison and Pearson's regression were applied.


Results: The rate of catheter-related bacteraemia was reduced from 1.25 to 0.15 per 1,000 catheter-days after the introduction of closed-system connectors with a neutral valve. A total of 100% of the catheters maintained desirable arterial and venous pressure values, 95.2% an adequate blood flow, and 40.3% achieved optimal dialysis dose, with lower performance in males.
Conclusions: The use of closed-system connectors with a neutral valve significantly decreased infections without affecting catheter function. Robust multicentre studies are needed to confirm effectiveness.

Keywords

central venous catheters haemodialysis catheter-related infections needleless connectors/neutral valve before and after controlled studies

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Copyright (c) 2025 Míriam Lladó-Barragán, Laia Reixach-Aumatell, Cristina Vázquez-Ros, Cristina Pena-García, Aurora Fontova-Almato, Alicia Rey-Miguel

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Lladó Barragán M, Reixach Aumatell L, Vázquez Ros C, Pena García C, Fontova Almato A, Rey Miguel A. Prevention of tunneled haemodialysis catheter-related dysfunction and bacteraemia using a closed-system connector with neutral valve: a quasi-experimental beforeafter study. Enferm Nefrol [Internet]. 2025 [cited 2025 Sep 30];28(2):[about 8 p.]. Available from: https://www.enfermerianefrologica.com/revista/article/view/4829
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