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Abstract
The first successful kidney transplant was performed in 1954 and was a live kidney transplant between identical twins at the Peter Bent Brigham Hospital in Boston1. This was historic as it helped to overcome the main barrier to the success of this treatment: rejection. From 1972 with the appearance of immunosuppressive drugs such as cyclosporine2 and years later, with the acceptance of diagnostic criteria of brain death, kidney transplantation from deceased donors has prevailed over living donor. The latest data published by the National Transplant Organisation (ONT), continues to show that the kidney transplant activity carried out in Spain has been mainly from cadaveric donors. In 2011, 312 live donor kidney transplants were performed, representing 12.5% of total kidney activity3. Although these figures are not very high, it is worth noting the progressive increase since 2000. Live kidney transplant activity is expected to continue to increase in Spain. The interest in promoting this type of donation is influenced by several clearly defined aspects: the good results obtained in survival4,5,6 and in quality of life7,8,9, the change in the demographic profile and comorbidity of the deceased donor, the improvement in donor safety and the insufficient availability of organs for transplant.
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Copyright (c) 2013 Miguel Ángel Hidalgo-Blanco, Mª Carmen Moreno-Arroyo
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References
- Murray JE, Merril JP, Hartwell Harrison J. Renal homotransplantations in identical twins. Surg Fo-rum 1995;VI:432-436.
- Borel JF, Feurer C, Gubler HU, Stahelin H. Biologi-cal effects of cyclosporin A: a new antilymphocyte agent. Agents Actions 1976: 468-475.
- Memoria de actividad de donación y trasplante 2011. Página web de la Organización Nacional de Trasplantes.Disponible en: último acceso: 9 de Febrero del 2013.
- Data on organ donation and transplantation. Organ Procurement Transplant Net-work Web site. Dispo-nible en: http://optn.transplant.hrsa.gov/latestDa-ta/rptStrat.asp. Último acceso: 8 de Febrero del 2013.
- Cecka JM. The UNOS Scientifi c Renal Transplant Registry. Clin Transpl 2001; 1-18.
- Solà R, Vela E, Cleries M, Guirado LI, Díaz JM, Facundo C, Deulofeu R. Living donor kidney trans-plantation in Catalonia: comparison with cadave-ric kidney donors. Transplant Proc 2007; 39 (7): 2208-9.
- Garcia MF, Andrade LG, Carvalho MF. Living kid-ney donors – a prospective study of quality of life before and after kidney donation. Clin Transplant. 2013 Jan;27(1):9-14.
- Coelho JC, Parolin MB, Baretta GA, Pimentel SK, De Freitas AC, Colman D. Donor quality of life after living donor liver transplantation. Arq Gastro-enterol 2005: 42: 83.
- Lumsdaine JA, Wray A, Power MJ et al. Higher qualityof live in living donor kidney transplanta-tion: prospective cohort study. Transpl Int 2005: 18: 975.
References
Murray JE, Merril JP, Hartwell Harrison J. Renal homotransplantations in identical twins. Surg Fo-rum 1995;VI:432-436.
Borel JF, Feurer C, Gubler HU, Stahelin H. Biologi-cal effects of cyclosporin A: a new antilymphocyte agent. Agents Actions 1976: 468-475.
Memoria de actividad de donación y trasplante 2011. Página web de la Organización Nacional de Trasplantes.Disponible en: último acceso: 9 de Febrero del 2013.
Data on organ donation and transplantation. Organ Procurement Transplant Net-work Web site. Dispo-nible en: http://optn.transplant.hrsa.gov/latestDa-ta/rptStrat.asp. Último acceso: 8 de Febrero del 2013.
Cecka JM. The UNOS Scientifi c Renal Transplant Registry. Clin Transpl 2001; 1-18.
Solà R, Vela E, Cleries M, Guirado LI, Díaz JM, Facundo C, Deulofeu R. Living donor kidney trans-plantation in Catalonia: comparison with cadave-ric kidney donors. Transplant Proc 2007; 39 (7): 2208-9.
Garcia MF, Andrade LG, Carvalho MF. Living kid-ney donors – a prospective study of quality of life before and after kidney donation. Clin Transplant. 2013 Jan;27(1):9-14.
Coelho JC, Parolin MB, Baretta GA, Pimentel SK, De Freitas AC, Colman D. Donor quality of life after living donor liver transplantation. Arq Gastro-enterol 2005: 42: 83.
Lumsdaine JA, Wray A, Power MJ et al. Higher qualityof live in living donor kidney transplanta-tion: prospective cohort study. Transpl Int 2005: 18: 975.