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Submitted
September 17, 2018
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September 17, 2018
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Abstract
Multiple myeloma is a hematological pathology characterized by a proliferation of plasma cells in the bone marrow, causing an excess production of free light chains, being this fact the main cause of renal failure.
Case report: We present two cases of patients aged 56 and 73 years with multiple myeloma with Lambda and Kappa chains and with acute renal failure. They were treated in the dialysis unit of the Rey Juan Carlos Hospital with long-term hemodialysis using the Filtryzer BK-2.1F filter.
Both required combined daily and long-term chemotherapy and hemodialysis with a wide-pore dialyzer. It was observed that with the hemodialysis sessions the light chains diminished considerably and that the two patients improved the glomerular filtration rate without needing hemodialysis sessions. The most frequent complication was the coagulation of the extracorporeal circuit.
The importance of initiating early diagnosis and treatment to reduce the risk of chronic renal failure is highlighted.
Case report: We present two cases of patients aged 56 and 73 years with multiple myeloma with Lambda and Kappa chains and with acute renal failure. They were treated in the dialysis unit of the Rey Juan Carlos Hospital with long-term hemodialysis using the Filtryzer BK-2.1F filter.
Both required combined daily and long-term chemotherapy and hemodialysis with a wide-pore dialyzer. It was observed that with the hemodialysis sessions the light chains diminished considerably and that the two patients improved the glomerular filtration rate without needing hemodialysis sessions. The most frequent complication was the coagulation of the extracorporeal circuit.
The importance of initiating early diagnosis and treatment to reduce the risk of chronic renal failure is highlighted.
Keywords
high cut-off dialyzer; free light chains; multiple myeloma; hemodialysis; acute renal failure; case report.
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How to Cite
1.
Garza Jiménez E, Piña Simón MD, Rojas Alfaro IM. Hemodialysis in Patients with Multiple Myeloma: A report of two cases. Enferm Nefrol [Internet]. 2018 [cited 2025 Apr 30];21(3):[about 6 p.]. Available from: https://www.enfermerianefrologica.com/revista/article/view/4102
