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May 28, 2025
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June 16, 2025
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June 30, 2025
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Abstract

Introduction: Treatment adherence in haemodialysis patients is a crucial aspect for improving clinical outcomes and quality of life.


Objectives: To identify the factors associated with treatment adherence in people on haemodialysis.


Material and Method: A scoping review was conducted. The search protocol was developed in the SciElo, PubMed, Scopus, ScienceDirect, EBSCO, and Cinahl databases, using the Boolean operators "AND," "OR," "NOT," relating the DeCS-MeSH search terms: "Treatment Adherence and Compliance" AND "Kidney Diseases" AND "Renal Dialysis."
Results: The review identified 36 articles, most from 2014, with 6 developed in Spain, 5 in Brazil and Iran, 4 in the United States, 3 in Indonesia and China, 2 in Australia and India, 1 in Colombia, Korea, Canada, Mexico, United Kingdom, and Turkey. Written in English, Spanish, and Portuguese. Adherence is influenced by biopsychosocial, economic, demographic, clinical, and psychological factors. Studies highlight the importance of education, economic stability, family relationships, mental health, medical team support, and educational strategies.


Conclusions: The complexity of treatment adherence in haemodialysis patients and the need for a comprehensive approach addressing multiple aspects are revealed. The importance of personalised educational programmes, socioeconomic support, effective communication with healthcare professionals, and personalised strategies to improve adherence is emphasised. These findings have important implications for designing interventions that improve quality of life and clinical outcomes in this population

Keywords

chronic kidney failure haemodialysis treatment adherence risk factors nursing care

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Copyright (c) 2025 Claudia Patricia Cantillo-Medina, Alix Yaneth Perdomo-Romero, Claudia Andrea Ramírez-Perdomo

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Author Biographies

Alix Yaneth Perdomo-Romero, Programa de Enfermería. Facultad de Salud. Universidad Surcolombiana. Huila. Colombia

Magister en Enfermería, Docente de tiempo completo Programa de Enfermería, Pregrado y post grado

Claudia Andrea Ramírez-Perdomo, Universidad Surcolombiana

Doctora en Enfermería, Docente de tiempoo completo en enfermería pregrado y postgrado

How to Cite
1.
Cantillo Medina CP, Perdomo Romero AY, Ramírez Perdomo CA. Factors associated with treatment adherence in people on haemodialysis. Enferm Nefrol [Internet]. 2025 [cited 2025 Aug 15];28(2):[about 15 p.]. Available from: https://www.enfermerianefrologica.com/revista/article/view/4764
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References

  1. Li P, García G, Siu L, Andreoli S, Fung W, Hradsky A, et al. Salud renal para todos en todas partes. Desde la prevención hasta la detección y el acceso equitativo a la atención. Rev Nefrol Dial Traspl [Internet]. 2020 [consultado 10 Ene 2024];40(1):1-13. Disponible en: https:/www.revistarenal. org.ar/index.php/rndt/article/view/502
  2. Ginarte GM, Domínguez EG, Marín DP. Enfermedad renal crónica, algunas consideraciones actuales. Multimed Revista Médica Granma [Internet]. 2020 [consultado 22 Feb 2024];24(2):464–9. Disponible en: http://scielo.sld.cu/pdf/mmed/v24n2/1028-4818-mmed-24-02-464.pdf
  3. Mansouri P, Sayari R, Dehghani Z, Hosseini FN. Comparison of the effect of multimedia and booklet methods on quality of life of kidney transplant patients: A randomized clinical trial study. Int J Community Based Nurs Midwifery. 2020;8(1):12-22.
  4. Durán BM. Informe de Diálisis y Trasplante 2014. XLIX Congreso Nacional de la Sociedad Española de Nefrología. A Coruña. 2019;73.
  5. Ojeda M, Caro I, Ojeda D, García A, García S, García S. Consulta de enfermería y adherencia terapéutica del paciente en hemodiálisis. Enferm Nefrol [Internet]. 2017 [consultado 10 Ene 2024];20(2):132-8. Disponible en: https://doi.org/10.4321/S2254-288420170000200006
  6. Murali KM, Mullan J, Roodenrys S, Hassan HC, Lam- bert K, Lonergan M. Strategies to improve dietary, fluid, dialysis or medication adherence in patients with end stage kidney disease on dialysis: A systematic review and meta-analysis of randomized intervention trials. PLoS One [Internet]. 2019 [consultado 2 Abr 2021];14(1):e0211479. Disponible en: https://doi.org/10.1371/journal.pone. 0211479
  7. Ohya, M, Iwashita, Y, Kunimoto, S, Mima, T, Negi, S, Shigematsu, T. An analysis of medication adherence and patient preference in long-term stable maintenance hemodialysis patients in Japan. Inter Med. 2019;58(18):2595-603. DOI: https://doi.org/10.2169/internalmedicine.2676-19
  8. Puigdemont N, Merino M. Adherencia terapéutica: factores modificadores y estrategias de mejora. Ars Pharmaceutica [Internet]. 2020 [consultado 1 Jun 2023];59(4). Disponible en: https://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S2340-98942018000400251
  9. Valle S. Factores de riesgo de no adherencia al tratamiento en pacientes mayores de un núcleo rural. Revista de la OFIL [Internet]. 2021 [consultado 1 Jun 2023];30(2). Disponible en: https://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1699-714X2020000200115
  10. Hald K, Larsen FB, Nilsen KM, Meillier LK, Johansen MB, Larsen ML, Christensen B, Nielsen CV. Medication adherence, biological and lifestyle risk factors in patients with myocardial infarction: a ten-year follow-up on socially differentiated cardiac rehabilitation. Scand J Prim Health Care, 2019;37 (2):182-90. DOI: https://doi.org/10.1080/02813432.2019.1608046
  11. Ceballos Casas MA, Girón Madroñero DI, Paz López PA, Ante Pantoja JD. Adherencia al tratamiento no farmacológico en pacientes con enfermedad renal crónica. Archivos Venezolanos de Farmacología y Terapéutica [Internet]. 2020 [consultado 1 Jun 2023];39(4). Disponible en: https://www.redalyc.org/journal/559/55965385016/55965385016.pdf
  12. Casares-Cid S, Goncalves-Vázquez PN, Alonso-González A, Remigio-Lorenzo MJ, Vázquez-Rivera J, Martínez-Ques AA. Relación entre calidad de vida, adherencia al tratamiento y nivel de conocimiento del paciente en hemodiálisis. Enferm Nefrol. 2022;25(2):140-8. DOI: https://doi.org/10.37551/52254-28842022015
  13. Armstrong R, Hall B, Doyle J, Waters E. Cochrane Update ‘Scoping the scope’ of a cochrane review. J Public Health (Bangkok). 2011;33(1). DOI: https://doi.org/10.1093/pubmed/fdr015
  14. Arksey H, O’Malley L. Scoping studies: Towards a methodological framework. Int J Soc Res Methodol Theory Pract. 2005;8(1):19-32. DOI: https://doi.org/10.1080/1364557032000119616
  15. Santamaría Olmo R. Programa de Habilidades en Lectura Crítica Espanol (CASPe). Nefrología [Internet]. 2017 [consultado 22 Feb 2024];9(1):100-1. Disponible en: https://www.revistanefrologia.com/es-programa-habilidades-lectura-critica-espanol-articulo-X1888970017612483
  16. Clarke V, Braun V. Teaching thematic analysis: Overcoming challenges and developing strategies for effective learning. The Psychologist 2013; 26:120-3.
  17. Torabi Khah M, Farsi Z, Sajadi SA. Comparing the effects of mHealth application based on micro-learning method and face-to-face training on treatment adherence and perception in haemodialysis patients: a randomised clinical trial. BMJ Open [Internet]. 2023 [consultado 17 Oct 2023];13(6):e071982. Disponible en: https://pubmed.ncbi.nlm.nih.gov/37270196/. DOI: https://doi.org/10.1136/bmjopen-2023-071982
  18. Mirzaei-Alavijeh M, Hamzeh B, Omrani H, Esmailli S, Khakzad S, Jalilian F. Determinants of medication adherence in hemodialysis patients: a cross-sectional study based on capability-opportunity-motivation and behavior model. BMC Nephrol. [Internet]. [consultado 14 Jun 2023];24(1):174. https://doi.org/10.1186/s12882-023-03231-0.PMID: 37316774; PMCID: PMC10266875 DOI: https://doi.org/10.1186/s12882-023-03231-0
  19. Dsouza B, Prabhu R, Unnikrishnan B, Ballal S, Mundkur S, Chandra Sekaran V, et al. Effect of Educational Intervention on Knowledge and Level of Adherence among Hemodialysis Patients: A Randomized Controlled Trial. Glob Health Epidemiol Genom [Internet]. 2023 [consultado 17 Oct 2023];4295613. Disponible en: https://pubmed.ncbi.nlm.nih.gov/37033597/. DOI: https://doi.org/10.1155/2023/4295613
  20. Sabouri F, Rambod M, Khademian Z. The effect of positive thinking training on hope and adherence to treatment in hemodialysis patients: a randomized controlled trial. BMC Psychol [Internet]. 2023 [consultado 17 Oct 2023];11(1):6. Disponible en: https://pubmed.ncbi.nlm.nih.gov/36624540/. DOI: https://doi.org/10.1186/s40359-023-01036-2
  21. Pereira C, Leite ICG. Fatores associados à não adesão ao regime terapêutico de pacientes em hemodiálise. Cad saúde colet [Internet]. 2022 [consultado 17 Oct 2023];30(3). Disponible en: https://www.scielo.br/j/cadsc/a/TVvHBHbL7VFVQbdXm3qTmdC/?lang=pt22. Kim H, Jeong I, Cho MK. Effect of Treatment Adherence Improvement Program in Hemodialysis Patients: A Systematic Review and Meta-Analysis. Int J Environ Res Public Health [Internet]. 2022 [consultado 17 Oct 2023];19(18):11657. Disponible en: https://pubmed.ncbi.nlm.nih.gov/36141929/.
  22. Wu R, Feng S, Quan H, Zhang Y, Fu R, Li H. Effect of Self-Determination Theory on Knowledge, Treatment Adherence, and Self-Management of Patients with Maintenance Hemodialysis. Contrast Media Mol Imaging [Internet]. 2022 [consultado 17 Oct 2023];(20):1416404. Disponible en: https://pubmed.ncbi.nlm.nih.gov/35935305/. DOI: https://doi.org/10.1155/2022/1416404
  23. Rivera E, Clark-Cutaia M, Schrauben S, Townsend R, Lash J, Hannan M, et al. Treatment Adherence in CKD and Support From Health care Providers: A Qualitative Study. Kidney Med [Internet]. 2022 [consultado 17 Oct 2023];4(11):100545. Disponible en: https://www.sciencedirect.com/science/article/pii/S2590059522001716 DOI: https://doi.org/10.1016/j.xkme.2022.100545
  24. Sheshadri A, Kittiskulnam P, Delgado C, Sudore R, Lai J, Johansen KL. Association of Cognitive Function Screening Results with Adherence and Performance in a Pedometer-Based Intervention. m J Nephrol [Internet]. 2021 [consultado 17 Oct 2023];52(5):420–8. Disponible en: https://pubmed.ncbi.nlm.nih.gov/33979802/. DOI: https://doi.org/10.1159/000516130
  25. Valsaraj B, Bhat S, Prabhu R, Kamath A. Follow-Up Study on the Effect of Cognitive Behaviour Therapy on Haemodialysis Adherence: A randomised controlled trial. Sultan Qaboos Univ Med J [Internet]. 2021 [consultado 17 Oct 2023];21(1):e58–65. Disponible en: https://pubmed.ncbi.nlm.nih.gov/33777424/. DOI: https://doi.org/10.18295/squmj.2021.21.01.008
  26. Arad M, Goli R, Parizad N, Vahabzadeh D, Baghaei R. Do the patient education program and nurse-led telephone follow-up improve treatment adherence in hemodialysis patients? A randomized controlled trial. BMC Nephrol [Internet]. 2021 [consultado 17 Oct 2023];22(1):119. Disponible en: https://pubmed.ncbi.nlm.nih.gov/33827478/. DOI: https://doi.org/10.1186/s12882-021-02319-9
  27. Anisa A, Didik GT, Bhisma M. Path Analysis on Factors Affecting the Use of Hemodialysis in Patients Chronic Renal Disease at Dr. Soehadi Prijonegoro Hospital Sragen, Central Java. JOURNAL OF HEALTH POLICY AND MANAGEMENT [Internet]. 2021 [consultado 17 Oct 2023];6(1). Disponible en: https://www.cabidigitallibrary.org/doi/pdf/10.5555/20210247404 DOI: https://doi.org/10.26911/thejhpm.2021.06.01.02
  28. Blumrosen C, Desta R, Cavanaugh K, Laferriere H, Bruce M, Norris K, et al. Interventions Incorporating Therapeutic Alliance to Improve Hemodialysis Treatment Adherence in Black Patients with End-Stage Kidney Disease (ESKD) in the United States: A Systematic Review. Patient Prefer Adherence [Internet]. 2020 [consultado 17 Oct 2023];17(14):1435–44. Disponible en: https://pubmed.ncbi.nlm.nih.gov/32884245/. DOI: https://doi.org/10.2147/PPA.S260684
  29. Yangöz S, Özer Z. Nursing Approach Based on Watson’s Theory of Human Caring in Treatment Adherence in Hemodialysis Patients. Bezmialem Science [Internet]. 2020 [consultado 17 Oct 2023;(8):189–95. Disponible en: https://bezmialemscience.org/archives/archive-detail/article-preview/nursing-approach-based-on-watsons-theory-of-human-/37325 DOI: https://doi.org/10.14235/bas.galenos.2019.3546
  30. Arenas Jiménez D, Navarro González J. How to improve adherence the captors of phosphorus on hemodialysis: Experience in real life with sucroferric oxyhydroxide. Nefrología (English Edition) [Internet]. 2020 [consultado 17 Oct 2023];40(6):640–6. Disponible en: https://www.sciencedirect.com/science/article/pii/S201325142030136X DOI: https://doi.org/10.1016/j.nefroe.2020.11.008
  31. Tayebi A, Einollahi B, Rahimi A, Sirati-Nir M. Non-adherence to Treatment Among Iranian Dialysis Patients, A Systematic Review. Iran J Kidney Dis [Internet]. 2019 [consultado 17 Oct 2023];13(6):347–61. Disponible en: https://pubmed.ncbi.nlm.nih.gov/31880581/.
  32. Hjemås B, Bøvre K, Mathiesen L, Lindstrøm J, Bjerknes K. Interventional study to improve adherence to phosphate binder treatment in dialysis patients. BMC Nephrol [Internet]. 2019 [consultado 17 Oct 2023];20(1):178. Disponible en: https://pubmed.ncbi.nlm.nih.gov/31101020/. DOI: https://doi.org/10.1186/s12882-019-1334-x
  33. Harish B, Ramesh C. Adherence to dietary and fluid restrictions among patients undergoing hemodialysis: An observational study. Clin Epidemiol Glob Health [Internet]. 2019 [consultado 17 Oct 2023];7(1):127–30. Disponible en: https://www.sciencedirect.com/science/article/pii/S2213398418301088 DOI: https://doi.org/10.1016/j.cegh.2018.05.003
  34. Wang J, Yue P, Huang J, Xie X, Ling Y, Jia L, et al. Nursing Intervention on the Compliance of Hemodialysis Patients with End-Stage Renal Disease: A Meta-Analysis. Blood Purif [Internet]. 2018 [consultado 17 Oct 2023];45(1–3):102–9. Disponible en: https://pubmed.ncbi.nlm.nih.gov/29241195/. DOI: https://doi.org/10.1159/000484924
  35. Lins S, et al. Adesão de portadores de doença renal crônica em hemodiálise ao tratamento estabelecido. Acta Paul Enferm [Internet]. 2018 [consultado 17 Oct 2023];31(1). Disponible en: https://www.scielo.br/j/ape/a/XrgGPyXqTQsBncc8zjTd5bc/?lang=pt DOI: https://doi.org/10.1590/1982-0194201800009
  36. Qazi H, Chen H, Zhu M. Factors influencing dialysis withdrawal: a scoping review. BMC Nephrol [Internet]. 2018 [consultado 18 Oct 2023];19(1):96. Disponible en: https://pubmed.ncbi.nlm.nih.gov/29699499/. DOI: https://doi.org/10.1186/s12882-018-0894-5
  37. Novaes Ferraz R, Godoy Maciel C, Borba A, Frazão I, França V. Percepção dos profissionais de saúde sobre os fatores para a adesão ao tratamento hemodialítico. REVISTA ENFERMAGEM UERJ [Internet]. 2017 [consultado 17 Oct 2023];25(0):e15504–e15504. Disponible en: https://www.e-publicacoes.uerj.br/enfermagemuerj/article/view/15504/24270 DOI: https://doi.org/10.12957/reuerj.2017.15504
  38. Ojeda Ramírez MD, Caro Rodríguez I, Ojeda Ramírez D, García Pérez A, García Hita S, García Marcos Sergio. Consulta de enfermería y adherencia terapéutica del paciente en hemodiálisis. Enferm Nefrol [Internet]. 2017 [consultado 17 Oct 2023];20(2):132–8. Disponible en: https://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S2254-28842017000200132&lang=pt DOI: https://doi.org/10.4321/S2254-288420170000200006
  39. Neto M, Moura A, Suassuna J. Renouncement of renal replacement therapy: withdrawal and refusal. J Bras Nefrol [Internet]. 2017 [consultado 17 Oct 2023];39(3):312–22. Disponible en: https://pubmed.ncbi.nlm.nih.gov/29044340/. DOI: https://doi.org/10.5935/0101-2800.20170054
  40. Endang SPN, Agus R, Hammad H. The compliance chronic renal failure patient on restrictions liquids in hemodialysis therapy. Journal Ners [Internet]. 2017 [consultado 17 Oct 2023];(1):24–30. Disponible en: https://ucm.on.worldcat.org/search/detail/8772642647?queryString=kw%3A%28Treatment%20Adherence%20and%20Compliance%29%20AND%20kw%3A%28Hemodialysis%29&expandSearch=false&translateSearch=false&databaseList=1672%2C1941%2C1953%2C2237%2C2259%2C2269%2C285%2C3036%2C3860%2C3867%2C3954%2C638&clusterResults=false&groupVariantRecords=true&changedFacet=content&year=2014..2023&content=openAccess&content=fullText&page=2
  41. Endah Karuniawati WS. Kepatuhan penggunaan obat dan kualitas hidup pasien hemodialisa di rs pku muhammadiyah yogyakarta periode maret 2015. Jurnal Farmasi Sains Dan Komunitas [Internet]. 2016 [consultado 17 Oct 2023];13(2):73–80. Disponible en: file:///C:/Users/ASUS/Downloads/Kepatuhan_Penggunaan_Obat_dan_Kualitas_Hidup_Pasie.pdf DOI: https://doi.org/10.24071/jpsc.2016.130205
  42. Villegas-Alzate JD, Vera-Henao S, Jaramillo-Monsalve MC, Jaramillo-Jaramillo LI, Martínez-Sánchez LM, Martínez-Domínguez GI, et al. El abandono de la adherencia en la terapia de reemplazo renal: una alarma en salud pública. Comunidad y Salud [Internet]. 2016 [consultado 17 Oct 2023];14(2). Disponible en: https://ve.scielo.org/scielo.phpscript=sci_arttext&pid=S169032932016000200006&lang=pt
  43. Hussain J, Flemming K, Murtagh F, Johnson MJ. Patient and health care professional decision-making to commence and withdraw from renal dialysis: a systematic review of qualitative research. Clin J Am Soc Nephrol [Internet]. 2015 [consultado 18 Oct 2023];10(7):1201–15. Disponible en: https://pubmed.ncbi.nlm.nih.gov/25943310/. DOI: https://doi.org/10.2215/CJN.11091114
  44. Ghimire S, Castelino R, Lioufas N, Peterson G, Zaidi ST. Nonadherence to Medication Therapy in Haemodialysis Patients: A Systematic Review. PLoS One [Internet]. 2015 [consultado 17 Oct 2023];4(10):e0144119. Disponible en: https://pubmed.ncbi.nlm.nih.gov/26636968/. DOI: https://doi.org/10.1371/journal.pone.0144119
  45. Huertas-Vieco MP, Pérez-García R, Albalate M, Sequera P de, Ortega M, Puerta Marta, et al. Factores psicosociales y adherencia al tratamiento farmacológico en pacientes en hemodiálisis crónica. Nefrología (Madrid) [Internet]. 2014 [consultado 17 Oct 2023];34(6). Disponible en: https://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0211-69952014000600008&lang=pt
  46. Murali K, Mullan J, Roodenrys S, Hassan H, Lambert K, Lonergan M. Strategies to improve dietary, fluid, dialysis or medication adherence in patients with end stage kidney disease on dialysis: A systematic review and meta-analysis of randomized intervention trials. PLoS One [Internet]. 2019 [consultado 18 Oct 2023];14(1):e0211479. Disponible en: https://pubmed.ncbi.nlm.nih.gov/30695068/. DOI: https://doi.org/10.1371/journal.pone.0211479
  47. Clark-Cutaia M, Ren D, Hoffman L, Burke L, Sevick MA. Adherence to hemodialysis dietary sodium recommendations: influence of patient characteristics, self-efficacy, and perceived barriers. J Ren Nutr [Internet]. 2014 [consultado 17 Oct 2023];24(2):92–9. Disponible en: https://pubmed.ncbi.nlm.nih.gov/24462498/. DOI: https://doi.org/10.1053/j.jrn.2013.11.007
  48. Rueda Velasco L, Reina Fernández R, Domínguez Berruezo M del C, Moreno Díaz I, García Frías Patricia. Análisis de la adherencia terapéutica en pacientes en hemodiálisis. Enfermería Nefrológica [Internet]. 2014 [consultado 17 Oct 2023];17(1):117. Disponible en: https://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S2254-28842014000500090
  49. Cazorla Santana MN, Rodríguez Díaz Dora. Grado de adherencia terapéutica a los fármacos del metabolismo óseo-mineral: ¿toman nuestros pacientes la medicación prescrita? Enfermería Nefrológica [Internet]. 2013 [consultado 17 Oct 2023];16(1). Disponible en: https://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S2254-28842013000100007&lang=pt DOI: https://doi.org/10.4321/S2254-28842013000100007
  50. Arenas MD, Pérez-García R, Bennouna M, Blanco A, Mauricio-Reatiga Ó, Prados M. D, et al. Mejoría del cumplimiento terapéutico en pacientes en hemodiálisis con mal control del fósforo y mala adherencia al tratamiento con captores: Estudio COMQUELFOS. Nefrología [Internet]. 2013 [consultado 18 Oct 2023];33(2):196–203. Disponible en: https://scielo.isciii.es/scielo.phpscript=sci_arttext&pid=S021169952013000200007&lang=pt
  51. Martins M, Silva L, Kraychete A, Reis D, Dias L, Schnitman G, et al. Potentially modifiable factors associated with non-adherence to phosphate binder use in patients on hemodialysis. BMC Nephrol [Internet]. 2013 [consultado 17 Oct 2023];3(14):208. Disponible en: https://pubmed.ncbi.nlm.nih.gov/24090377/. DOI: https://doi.org/10.1186/1471-2369-14-208

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