Main Article Content
Abstract
Introduction: Dysfunction and infections are the most frequent causes of removal of tunneled central venous hemodialysis catheters.
Objective: To analyse whether the lateral or medial orientation of the catheter’s arterial line influences early dysfunction.
Material and Method: Prospective observational study of 24 months’ duration. Adult hemodialysis patients undergoing first-time cannulation of a tunneled venous catheter of the Palindrome® or Bioflo Duramax® model were included. Variables: arterial line orientation, catheter model, socio-demographic and clinical characteristics, blood pump flows, arterial and venous pressures, conductance, complications and defining characteristics of early dysfunction.
Results: A total of 178 patients were studied, mean age 64.4±15.1 years; 108 men; 105 with arterial line in lateral orientation and 73 with medial orientation. There was early dysfunction in 30 cases (16.9%): lateral orientation 63.3% (n=19) vs medial orientation 36.7% (n=11), (p=0.621). In all cases with early dysfunction, it was necessary to reverse the catheter line to the extracorporeal circuit connections, due to a pump flow< 250 ml/min, being more frequent in Palindrome® catheters with arterial line in lateral orientation, 87.5% (n=7) vs medial orientation 12.5% (n=1), (p=0.063).
Conclusions: In our sample, arterial luminal orientation did not influence early catheter dysfunction.
Keywords
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Copyright (c) 2022 Juan Manuel Manzano Angua

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References
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- Pisoni R, Young E, Dykstra D, Greenwood R., Hecking E., Gillespie B et al.Vascular access use in Europe and the United States: Results from the DOPPS. Kidney International 2002;61:305-16. DOI: https://doi.org/10.1046/j.1523-1755.2002.00117.x
- Rodríguez JA, López J, Piera L. El acceso vascular en España: análisis de su distribución, morbilidad y sistemas de monitorización. Nefrología 2001;21(1):45-51.
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- Trerotola SO, Johnson MS, Harris VJ, Shah H, Ambrosius WT, McKusky MA, et al. Outcome of tunnelled hemodialysis catheters placed via the right internal jugular vein by interventional radiologists. Radiology. 1997;203:489-93. DOI: https://doi.org/10.1148/radiology.203.2.9114110
- Hemmelgarn BR, Moist LM, Lok CE, et al. Prevention of dialysis catheter malfunction with recombinant tissue plasminogen activator. N Engl J Med. 2011;364(4):303-12. DOI: https://doi.org/10.1056/NEJMoa1011376
- Donati G, Colì L, Cianciolo G, et al. Thrombosis of tunneledcuffed hemodialysis catheters: treatment with high-dose urokinase lock therapy. Artif Organs 2012;36:21-8. DOI: https://doi.org/10.1111/j.1525-1594.2011.01290.x
- Bonkain F, Van Hulle F, Janssens P, et al. Urokinasecontaining locking solution in the prevention of dialysiscatheter dysfunction: a double blind randomized controlled trial. J Vasc Access 2017;18:436-42. DOI: https://doi.org/10.5301/jva.5000737
- Little MA, O”Riordan A, Lucey B, et al. A prospective study of complications associated with cuffed, tunneled haemodialysis catheters. Nephrol Dial Transplant 2001;16:2194-200. DOI: https://doi.org/10.1093/ndt/16.11.2194
- Ponikvar R, Buturovi-Ponikvar J. Temporary hemodialysis catheters as a long-term vascular access in chronic hemodialysis patients. Ther Apher Dial 2005;9:250-3. DOI: https://doi.org/10.1111/j.1774-9987.2005.00265.x
- NKF/DOQI. Clinical Practice Guidelines and Clinical Practice Recommendations for 2006 Updates: Hemodialysis Adequacy, Peritoneal Dialysis Adequacy and Vascular Access. Am J Kidney Dis 2006;48(Suppl 1):S1-S322.
- Faintuch S, Salazar GM. Malfunction of dialysis catheters: management of fibrin sheath and related problems. Tech Vasc Interv Radiol 2008;11:195-200. DOI: https://doi.org/10.1053/j.tvir.2008.09.008
- Ibeas J, Roca-Teyb R, Vallespínc J, Crespo R. Ochando, Cobo JL et al. Grupo Español Multidisciplinar del Acceso Vascular (GEMAV). Guía Clínica Española del Acceso Vascular para Hemodiálisis. Enferm Nefrol. 2018; 21(Supl 1):S6-198. DOI: https://doi.org/10.4321/S2254-28842018000500001
- Lok CE, Huber TS, Lee T, et al; KDOQI Vascular Access Guideline Work Group. KDOQI clinical practice guideline for vascular access: 2019 update. Am J Kidney Dis. 2020;75(4)(Suppl 2):S1-164. DOI: https://doi.org/10.1053/j.ajkd.2019.12.001
- Besarab A, Pandey R. Catheter management in hemodialysis patients: delivering adequate flow. Clin J Am Soc Nephrol 2011;6:227-34. DOI: https://doi.org/10.2215/CJN.04840610
- Heberlein W. Principles of Tunneled Cuffed Catheter Placement. Tech Vasc Interv Radiol 2011;14:192-7. DOI: https://doi.org/10.1053/j.tvir.2011.05.008
- Hoshal VL Jr, Ause RG, Hoskins PA. Fibrin sleeve formation on indwelling subclavian central venous catheters. Arch Surg 1971; 102:353-8. DOI: https://doi.org/10.1001/archsurg.1971.01350040115023
- Silberzweig JE, Sacks D, Khorsandi AS, Bakal CW. Society of Interventional Radiology Technology Assessment Committee. Reporting Standards for central Venous Access. J Vasc Interv Radiol 2003;14:S443-52. DOI: https://doi.org/10.1097/01.RVI.0000094617.61428.bc
- Apsner R, Sunder-Plassmann G, Muhm M,Druml W. Alternative puncture site for im-plantable permanent haemodialysis cathe-ters. Nephrol Dial Transplant 1996;11:2293-5. DOI: https://doi.org/10.1093/oxfordjournals.ndt.a027151
- Paraíso V, Merino JL, Ibeas J. Nefrología al día. Catéteres tunelizados para Hemodiálisis. Disponible en: https://www.nefrologiaaldia.org/427.
- Tang YW, Santerre JP, Labow RS, Taylor DG. Use of surface-modifying macromolecules to enhance the biostability of segmented polyurethanes. J Biomed Mater Res 1997;35(3):371-81. DOI: https://doi.org/10.1002/(SICI)1097-4636(19970605)35:3<371::AID-JBM11>3.0.CO;2-I
- Jahangir AR, McClung WG, Cornelius RM, McCloskey CB, Brash JL, Santerre JP. Fluorinated surface-modifying macromolecules: modulating adhesive protein and platelet interactions on a polyether-urethane. J Biomed Mater Res 2002;60(1):135-47. DOI: https://doi.org/10.1002/jbm.10033
- Massa TM, Yang ML, Ho JY, Brash JL, Santerre JP. Fibrinogen surface distribution correlates to platelet adhesion pattern on fluorinated surface-modified polyetherurethane. Biomaterials 2005;26(35):7367-76. DOI: https://doi.org/10.1016/j.biomaterials.2005.05.063
- Griffiths RI, Newsome BB, Block GA, et al. Patterns of Hemodialysis Catheter Dysfunction Defined According to National Kidney Foundation Guidelines As Blood Flow <300 ml/min. Int J Nephrol 2011;2011:891259. DOI: https://doi.org/10.4061/2011/891259
- Kosa SD, Ye C, Thabane L, et al. Predicting tissue plasminogen activator use and success in in-center hemodialysis patients. J Vasc Access 2018;19:146-52. DOI: https://doi.org/10.5301/jva.5000785
- Salvador García J, Gómez Valdés J, Casula E, Magán Martín A, Ruiz Guanter A, Lonjedo Vicent E. Diagnosis and treatment of late catheter dysfunction. Revista intervencionismo 2019;19(4):160-6.
- Carson RC, Kiaii M, MacRae JM. Urea clearance in dysfunctional catheters is improved by reversing the line position despite increased access recirculation. Am J Kidney Dis 2005;45(5):883-90. DOI: https://doi.org/10.1053/j.ajkd.2005.01.029
- Moya C, Fernández M, Ibeas J, Alcaraz J, Mañé N, Yuste E, et al. Monitorización sistemática del catéter permanente: una herramienta útil en el estudio de la tasa de infección y disfunción en dos tipos de catéteres. Rev Soc Esp Enferm Nefrol 2006;9(3):165-71. DOI: https://doi.org/10.4321/S1139-13752006000300003
- Crehuet I, Méndez P, Mulero T, Bernárdez M, Jiménez A, Toribio B. Recirculación de la sangre durante la sesión de hemodiálisis en el catéter tunelizado PalindromeTM. Rev Enferm Nefro 2012;15(1):22-7. DOI: https://doi.org/10.4321/S2254-28842012000100004
- Andreu-Periz D, Ochando-García A, Limón-Cáceres E. Experiencias de vida y soporte percibido por las enfermeras de las unidades de hemodiálisis hospitalaria durante la pandemia de COVID 19 en España. Enferm Nefrol 2020;23(2).148-59. DOI: https://doi.org/10.37551/S2254-28842020022
References
Lorenzo V, Martin M, Rufino M, Hernández D, Torres A y Ayus JC. Predialysis nephrologic care and a functioning arteriovenous fistula at entry are associated with better survival in incident hemodialysis patients: an observational cohort study. Am J Kidney Dis. 2004 Jun; 43(6):999-1007. DOI: https://doi.org/10.1053/j.ajkd.2004.02.012
Bradbury BD, Fissell RB, Albert JM y col. Predictors of early mortality among incident US hemodialysis patients in the Dialysis Outcomes and Practice Patterns Study (DOPPS). Clin J Am Soc Nephrol. 2007 Jan; 2(1):89-99. Epub 2006 Nov 29. DOI: https://doi.org/10.2215/CJN.01170905
Pisoni R, Young E, Dykstra D, Greenwood R., Hecking E., Gillespie B et al.Vascular access use in Europe and the United States: Results from the DOPPS. Kidney International 2002;61:305-16. DOI: https://doi.org/10.1046/j.1523-1755.2002.00117.x
Rodríguez JA, López J, Piera L. El acceso vascular en España: análisis de su distribución, morbilidad y sistemas de monitorización. Nefrología 2001;21(1):45-51.
Castro de P, Muñoz JM, Egea JJ. “Informe 2017, Sistema de Información de la Coordinación Autonómica de Trasplantes de Andalucía (SICATA). Subsistema de Insuficiencia Renal Crónica”. Consejería de Salud. Servicio Andaluz de Salud. Dirección General de Asistencia Sanitaria y Resultados en Salud. Coordinación Autonómica de Trasplantes. 2018. p. 42.
Castro de P, Muñoz JM, Egea JJ. “Informe 2020, Sistema de Información de la Coordinación Autonómica de Trasplantes de Andalucía (SICATA). Subsistema de Insuficiencia Renal Crónica”. Consejería de Salud. Servicio Andaluz de Salud. Dirección General de Asistencia Sanitaria y Resultados en Salud. Coordinación Autonómica de Trasplantes. 2018. p. 43.
Trerotola SO, Johnson MS, Harris VJ, Shah H, Ambrosius WT, McKusky MA, et al. Outcome of tunnelled hemodialysis catheters placed via the right internal jugular vein by interventional radiologists. Radiology. 1997;203:489-93. DOI: https://doi.org/10.1148/radiology.203.2.9114110
Hemmelgarn BR, Moist LM, Lok CE, et al. Prevention of dialysis catheter malfunction with recombinant tissue plasminogen activator. N Engl J Med. 2011;364(4):303-12. DOI: https://doi.org/10.1056/NEJMoa1011376
Donati G, Colì L, Cianciolo G, et al. Thrombosis of tunneledcuffed hemodialysis catheters: treatment with high-dose urokinase lock therapy. Artif Organs 2012;36:21-8. DOI: https://doi.org/10.1111/j.1525-1594.2011.01290.x
Bonkain F, Van Hulle F, Janssens P, et al. Urokinasecontaining locking solution in the prevention of dialysiscatheter dysfunction: a double blind randomized controlled trial. J Vasc Access 2017;18:436-42. DOI: https://doi.org/10.5301/jva.5000737
Little MA, O”Riordan A, Lucey B, et al. A prospective study of complications associated with cuffed, tunneled haemodialysis catheters. Nephrol Dial Transplant 2001;16:2194-200. DOI: https://doi.org/10.1093/ndt/16.11.2194
Ponikvar R, Buturovi-Ponikvar J. Temporary hemodialysis catheters as a long-term vascular access in chronic hemodialysis patients. Ther Apher Dial 2005;9:250-3. DOI: https://doi.org/10.1111/j.1774-9987.2005.00265.x
NKF/DOQI. Clinical Practice Guidelines and Clinical Practice Recommendations for 2006 Updates: Hemodialysis Adequacy, Peritoneal Dialysis Adequacy and Vascular Access. Am J Kidney Dis 2006;48(Suppl 1):S1-S322.
Faintuch S, Salazar GM. Malfunction of dialysis catheters: management of fibrin sheath and related problems. Tech Vasc Interv Radiol 2008;11:195-200. DOI: https://doi.org/10.1053/j.tvir.2008.09.008
Ibeas J, Roca-Teyb R, Vallespínc J, Crespo R. Ochando, Cobo JL et al. Grupo Español Multidisciplinar del Acceso Vascular (GEMAV). Guía Clínica Española del Acceso Vascular para Hemodiálisis. Enferm Nefrol. 2018; 21(Supl 1):S6-198. DOI: https://doi.org/10.4321/S2254-28842018000500001
Lok CE, Huber TS, Lee T, et al; KDOQI Vascular Access Guideline Work Group. KDOQI clinical practice guideline for vascular access: 2019 update. Am J Kidney Dis. 2020;75(4)(Suppl 2):S1-164. DOI: https://doi.org/10.1053/j.ajkd.2019.12.001
Besarab A, Pandey R. Catheter management in hemodialysis patients: delivering adequate flow. Clin J Am Soc Nephrol 2011;6:227-34. DOI: https://doi.org/10.2215/CJN.04840610
Heberlein W. Principles of Tunneled Cuffed Catheter Placement. Tech Vasc Interv Radiol 2011;14:192-7. DOI: https://doi.org/10.1053/j.tvir.2011.05.008
Hoshal VL Jr, Ause RG, Hoskins PA. Fibrin sleeve formation on indwelling subclavian central venous catheters. Arch Surg 1971; 102:353-8. DOI: https://doi.org/10.1001/archsurg.1971.01350040115023
Silberzweig JE, Sacks D, Khorsandi AS, Bakal CW. Society of Interventional Radiology Technology Assessment Committee. Reporting Standards for central Venous Access. J Vasc Interv Radiol 2003;14:S443-52. DOI: https://doi.org/10.1097/01.RVI.0000094617.61428.bc
Apsner R, Sunder-Plassmann G, Muhm M,Druml W. Alternative puncture site for im-plantable permanent haemodialysis cathe-ters. Nephrol Dial Transplant 1996;11:2293-5. DOI: https://doi.org/10.1093/oxfordjournals.ndt.a027151
Paraíso V, Merino JL, Ibeas J. Nefrología al día. Catéteres tunelizados para Hemodiálisis. Disponible en: https://www.nefrologiaaldia.org/427.
Tang YW, Santerre JP, Labow RS, Taylor DG. Use of surface-modifying macromolecules to enhance the biostability of segmented polyurethanes. J Biomed Mater Res 1997;35(3):371-81. DOI: https://doi.org/10.1002/(SICI)1097-4636(19970605)35:3<371::AID-JBM11>3.0.CO;2-I
Jahangir AR, McClung WG, Cornelius RM, McCloskey CB, Brash JL, Santerre JP. Fluorinated surface-modifying macromolecules: modulating adhesive protein and platelet interactions on a polyether-urethane. J Biomed Mater Res 2002;60(1):135-47. DOI: https://doi.org/10.1002/jbm.10033
Massa TM, Yang ML, Ho JY, Brash JL, Santerre JP. Fibrinogen surface distribution correlates to platelet adhesion pattern on fluorinated surface-modified polyetherurethane. Biomaterials 2005;26(35):7367-76. DOI: https://doi.org/10.1016/j.biomaterials.2005.05.063
Griffiths RI, Newsome BB, Block GA, et al. Patterns of Hemodialysis Catheter Dysfunction Defined According to National Kidney Foundation Guidelines As Blood Flow <300 ml/min. Int J Nephrol 2011;2011:891259. DOI: https://doi.org/10.4061/2011/891259
Kosa SD, Ye C, Thabane L, et al. Predicting tissue plasminogen activator use and success in in-center hemodialysis patients. J Vasc Access 2018;19:146-52. DOI: https://doi.org/10.5301/jva.5000785
Salvador García J, Gómez Valdés J, Casula E, Magán Martín A, Ruiz Guanter A, Lonjedo Vicent E. Diagnosis and treatment of late catheter dysfunction. Revista intervencionismo 2019;19(4):160-6.
Carson RC, Kiaii M, MacRae JM. Urea clearance in dysfunctional catheters is improved by reversing the line position despite increased access recirculation. Am J Kidney Dis 2005;45(5):883-90. DOI: https://doi.org/10.1053/j.ajkd.2005.01.029
Moya C, Fernández M, Ibeas J, Alcaraz J, Mañé N, Yuste E, et al. Monitorización sistemática del catéter permanente: una herramienta útil en el estudio de la tasa de infección y disfunción en dos tipos de catéteres. Rev Soc Esp Enferm Nefrol 2006;9(3):165-71. DOI: https://doi.org/10.4321/S1139-13752006000300003
Crehuet I, Méndez P, Mulero T, Bernárdez M, Jiménez A, Toribio B. Recirculación de la sangre durante la sesión de hemodiálisis en el catéter tunelizado PalindromeTM. Rev Enferm Nefro 2012;15(1):22-7. DOI: https://doi.org/10.4321/S2254-28842012000100004
Andreu-Periz D, Ochando-García A, Limón-Cáceres E. Experiencias de vida y soporte percibido por las enfermeras de las unidades de hemodiálisis hospitalaria durante la pandemia de COVID 19 en España. Enferm Nefrol 2020;23(2).148-59. DOI: https://doi.org/10.37551/S2254-28842020022