Diálisis peritoneal automática adaptada: un método de prescripción eficaz, eficiente y seguro

Abstract

The aim of this study is to analyze results obtained following the introduction of the adapted automated peritoneal dialysis, in a group of patients in conventional automated peritoneal dialysis program using bicarbonate-buffered dialysate. Design trial in experimental phase, which was conducted in the months from February and December 2013, in the unit of peritoneal dialysis in the Hospital Clinic of Barcelona. Study subjects were 12 patients, 7 women and 5 men, in conventional automated peritoneal dialysis modality. Mean age 58±12 years (range: 34-71). The study assessed two automated peritoneal dialysis prescriptions. This study was started with conventional dialysis for three months. Then, dialysis prescription was modified, and adapted was applied during same interval of time. And finally, conventional dialysis for three months. The same total volume of dialysate, the same duration, and the same 1,5% glucose bicarbonatebuffered dialysate, were prescribed in both modalities. Only dwell time and fill volume were modified, when dialysis modality was changed. All patients, on dry day. Variables at the beginning of the study, and at each change of prescription were seldom monitored. Outcomes for conventional dialysis: Kt/v=2,3±0,2, creatinine clearance=63±8l/week, and ultrafiltration=842±110ml. For dialysis adapted, Kt/v=2,8±0,2, creatinine clearance=74±9l/week, and ultrafiltration=982±123ml. Adapted dialysis allows appropriate treatment efficiency, improves adequacy of dialysis and ultrafiltration parameters; being safe and comfortable for the patient.